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Floyd Landis: He won the Tour de France in 2006, and his urine test came back with results of high testosterone. That means he's either getting close to his best years, or he's not. I don't know the difference any more. Brett McKay: That's interesting. Talk a little bit about what you think is driving testosterone. Nate Silver: This is a very, very, complicated subject. We're not talking about some kind of high-grade steroid. We're talking about some kind of guy who has been taking a substance that increases their testosterone. That's not the only factor. It could be the size of their penis because, I think it can be true that bigger penises have a higher risk of testosterone getting into their system. I think we don't know how much of the increase in testosterone is related to that. It could also be that there is a hormonal response to the drug because testosterone is a very potent anabolic steroid that's produced by the pituitary gland, which I was always taught is the only place where the anabolic response occurs. The adrenal would then be releasing adrenaline. There's an effect by the body that causes the pituitary gland to make the hormone, and that increases the anabolic response that happens in the gonads. And the pituitary gland can adjust the amount of the hormone depending on whether that hormone is coming in the pituitary through the kidneys or something else. Whatever that is is a part of it. So there are a lot of things that could be going on besides the steroid use, like genetics, the environment, and diet, and I mean, there are a lot of other factors going on. And so, in fact, one thing that's consistent among people that have been tested more frequently is that, they have higher levels of testosterone in the blood. So maybe they were in their 30s that have now gone on to have a lot higher testosterone. Brett McKay: Let's talk about the impact of testosterone on pregnancy. Obviously, most men take testosterone for testosterone. It's not like, "OK, you see, you want my dick." It's like, "You just put that hormone here so you can get this." Nate Silver: Exactly, exactly. And what has happened is this is a situation where there are different types of people who could benefit from it. If you read some of the studies that have been done—there's one, like, which looked at people who have had their ovaries removed because they have high testosterone levels. And then the other study— Similar articles: